BMSC13010 - Pharmacology
Term 1 - 2017


All details in this unit profile for BMSC13010 have been officially approved by CQUniversity and represent a learning partnership between the University and you (our student). The information will not be changed unless absolutely necessary and any change will be clearly indicated by an approved correction included in the profile.

Overview

This unit enables you to develop an advanced knowledge and understanding of the fundamental principles of basic and clinical pharmacology including the way drugs interact with cells and the body. The mechanism of action of major drug classes used in the treatment of disorders affecting the autonomic nervous system, the gastrointestinal tract, cardiovascular and pulmonary systems and central nervous system will be examined at the drug-receptor level. Pharmacokinetics, receptor selectivity, efficacy and the optimum route of administration of pharmaceuticals will also be studied. You will be required to demonstrate critical analysis of this content and align this with current practice in your respective courses.

Details

Career Level Undergraduate
Unit Level Level 3
Credit Points 6
Student Contribution Band 2
Fraction of Full-Time Student Load 0.125

Pre-requisites or Co-requisites

Pre-requisite

CG93 Medical Science and CG95 Paramedic Science:

BMED19003 Clinical Biochemistry OR BMSC12010 Clinical Biochemistry

CB77 Bachelor of Science (Chiropractic):

BMSC11005 Foundations of Biochemistry AND BMSC12007 Neurological Physiology and Measurement AND MBIO12013 Microbiology for Health Care AND CHIR12002 Neuroanatomy and Systemic Pathology

CB86 Bachelor of Podiatry Practice (Honours):

ALLH11001, ALLH11005, HLTH11027, PSYC11010, ALLH11004, ALLH12007, ALLH11006 and HLTH12028

Attendance Requirements

All on-campus students are expected to attend scheduled classes – in some units, these classes are identified as a mandatory (pass/fail) component and attendance is compulsory. International students, on a student visa, must maintain a full time study load and meet both attendance and academic progress requirements in each study period (satisfactory attendance for International students is defined as maintaining at least an 80% attendance record).

Offerings

Term 1 - 2017
  • Mixed Mode
  • Rockhampton

Website

This unit has a website, within the Moodle system, which is available two weeks before the start of term. It is important that you visit your Moodle site throughout the term. Go to Moodle

Recommended Student Time Commitment

Each 6-credit Undergraduate unit at CQUniversity requires an overall time commitment of an average of 12.5 hours of study per week, making a total of 150 hours for the unit.

Class Timetable

Assessment Overview

Assessment Task Weighting
1. Written Assessment 10%
2. Written Assessment 15%
3. Written Assessment 25%
4. Examination 50%

This is a graded unit: your overall grade will be calculated from the marks or grades for each assessment task, based on the relative weightings shown in the table above. You must obtain an overall mark for the unit of at least 50%, or an overall grade of ‘pass’ in order to pass the unit. If any ‘pass/fail’ tasks are shown in the table above they must also be completed successfully (‘pass’ grade). You must also meet any minimum mark requirements specified for a particular assessment task, as detailed in the ‘assessment task’ section (note that in some instances, the minimum mark for a task may be greater than 50%). Consult the University’s Grades and Results Procedures for more details of interim results and final grades.

All University policies are available on the IMPortal.

You may wish to view these policies:

  • Grades and Results Procedure
  • Assessment Policy and Procedure (Higher Education Coursework)
  • Review of Grade Procedure
  • Academic Misconduct Procedure
  • Monitoring Academic Progress (MAP) Policy and Procedure – Domestic Students
  • Monitoring Academic Progress (MAP) Policy and Procedure – International Students
  • Refund and Excess Payments (Credit Balances) Policy and Procedure
  • Student Feedback – Compliments and Complaints Policy and Procedure
  • Acceptable Use of Information and Communications Technology Facilities and Devices Policy and Procedure

This list is not an exhaustive list of all University policies. The full list of University policies are available on the IMPortal.

Feedback, Recommendations and Responses

Every unit is reviewed for enhancement each year. At the most recent review, the following staff and student feedback items were identified and recommendations were made.

Feedback Source Recommendation
Key learning outcomes were not highlighted during the lectures. course evaluation Key learning outcomes will be presented at the end of each lecture.
Details about assessment were vague course evlauation Provide a short video for each assessment item discussing requirements and known areas of concern for students.
On successful completion of this unit, you will be able to:
  1. Recognise and describe the differing ways in which drugs and chemicals act quantitatively and qualitatively on living organisms.
  2. Recall and explain the basic priciples of pharmacology - pharmacodynamics, pharmacokinetics, drug design and clinical trials.
  3. Recall and classify the major groups of medicines with respect to pathophysiology, their actions and therapeutic applications for medical science, paramedic science and podiatry practice (including local and general anaesthesia, cardiovascular, CNS, gastrointestinal, antimicrobial, respiratory and endocrine).
  4. Understand how pharmacological laboratory experiments are conducted by using computer aided learning modules, and interpret the results from these experiments (tables/graphs).
  5. Appraise the scientific literature relating to drugs and medicines and communicate this knowledge to your peers

Alignment of Assessment Tasks to Learning Outcomes

Assessment Tasks Learning Outcomes
1 2 3 4 5
1 - Written Assessment  
2 - Written Assessment    
3 - Written Assessment    
4 - Examination    

Alignment of Graduate Attributes to Learning Outcomes

  • Introductory Level
  • Intermediate Level
  • Graduate Level
Graduate Attributes Learning Outcomes
1 2 3 4 5
1. Communication  
2. Problem Solving
3. Critical Thinking
4. Information Literacy        
5. Team Work        
6. Information Technology Competence      
7. Cross Cultural Competence        
8. Ethical practice      

Alignment of Assessment Tasks to Graduate Attributes

  • Introductory Level
  • Intermediate Level
  • Graduate Level
Assessment Tasks Graduate Attributes
1 2 3 4 5 6 7 8
1 - Written Assessment      
2 - Written Assessment          
3 - Written Assessment
4 - Examination          

Prescribed Textbooks

Rang & Dale's Pharmacology
Author/s: Rang, HP, Ritter, JM, Flower, RJ & Henderson, G Year: 2015
Edition: 8th edn revised Publisher: Churchill Livingstone - Elsevier
City: London
Country: UK
View textbooks at the CQUniversity Bookshop

IT Resources

You will need access to the following IT resources:
  • CQUniversity Student Email
  • Internet
  • Unit Website (Moodle)
  • Computer-aided learning modules (CALs)
All submissions for this unit must use the American Psychological Association (APA) referencing style (details can be obtained here), OR Harvard (author-date) referencing style (details can be obtained here). For further information, see the Assessment Tasks below.
Unit CoordinatorAndrew Fenning (a.fenning@cqu.edu.au)
Note: Check the Term-Specific section for any additional contact information provided by the teaching team
Week Begin Date Module/Topic Chapter Events and Submissions
Week 1 06-03-2017

Drug-receptor interactions/Drug targets/Signal transduction (Lectures 1-3)

Online course material and PowerPoint notes/lecture videos

Week 2 13-03-2017

Pharmacokinetcs (Lectures 4-5); Clinical Trials (Lecture 6)

Online course material and PowerPoint notes/lecture videos

Week 3 20-03-2017

Autonomic Pharmacology (Lectures 7-8); Cardiovascular 1 (Lecture 9)

Online course material and PowerPoint notes/lecture videos

Week 4 27-03-2017

Cardiovascular 2-4 (Lectures 10-12)

Online course material and PowerPoint notes/lecture videos

Week 5 03-04-2017

CNS Pharmacology 1-3 (depression, anaesthesia, psychosis, ageing) (Lectures 13-15)

Online course material and PowerPoint notes/lecture videos

Written Assessment - Drug Poster Due Friday (07 Apr 17) 11:00 PM AEST
Vacation Week 10-04-2017
Week 6 17-04-2017

CNS - drugs of abuse, analgesia and anaesthesia (Lectures 16-18)

Online course material and PowerPoint notes/lecture videos

Week 7 24-04-2017 Antibiotics, antifungals and antiseptics (Lectures 19-21) Online course material and PowerPoint notes/lecture videos
Week 8 01-05-2017 Obesity, gastrointestinal, respiratory and endocrine pharmacology (Lectures 22-24) Online course material and PowerPoint notes/lecture videos
Written Assessment - Computer-aided learning practicals Due Thursday (04 May 17) 11:00 PM AEST
Week 9 08-05-2017

No lectures - revision

Week 10 15-05-2017

No lectures - revision

Written Assessment - complex reasoning Due Friday (19 May 17) 11:00 PM AEST
Week 11 22-05-2017

No lectures - revision

Week 12 29-05-2017

No lectures - revision

Review/Exam Week 05-06-2017
Exam Week 12-06-2017

1 Written Assessment

Assessment Title Written Assessment - Drug Poster
Task Description

In the second week of term, students will be randomly allocated the name of a drug, chemical or substance of abuse. Your task is to thoroughly research your given compound using journal article sources and other reference material to produce a poster summarising your findings. Assistance in the production of the poster is provided in the course Moodle site. The poster should be completed in PowerPoint or an alternative poster designing program. Students please note that pharmaceutical company Internet sources should only be used sparingly – you need to research primary literature material for the most recent scientific studies. This item is to be submitted electronically via Moodle. Examples of “typical” posters will be provided on Moodle. Where possible your drug will be allocated to have relevance to your discipline area (not always possible).

Assessment Due Date Week 5 Friday (07-Apr-2017) 11:00 PM AEST
Return Date to Students Week 6 Friday (21-Apr-2017)
Weighting 10%
Assessment Criteria

The following criteria and marking scheme will be used to evaluate the poster:

Marks Criteria
Content 30 Information covered should include clinical uses, development and clinical trials, toxicology, cellular mechanisms of action, side effects and interactions, pharmacokinetics and comparisons with other drugs or toxins where appropriate. Information must be concise and easy to comprehend.
Research 20 Intensive information searching outside of the Study Guide and textbook should be evident. Research material used should consist primarily of articles from refereed journals, textbooks and some Internet sources. You should also include interesting or novel findings about your drug/chemical.
Organisation 10 The content of the poster should be concise and separated into defined sections. All posters should have a clear heading/title with the author’s name and affiliation underneath in addition to the following sections:
Introduction/Pharmacology/Pharmacokinetics/Toxicology/
Conclusions/References
References 10 All sources (including Internet resources) should be listed in a small print at the end of the poster. The reference list should be constructed according to the “Harvard” style as described in the following website: http://www.cqu.edu.au/referencing
Presentation 30 The poster should have high reader impact. Good use of colour schemes and font styles and sizes should be evident. Content should be clearly written with a high quality of English expression (spelling, grammar). Bullet points should be used where appropriate. Abbreviations should be explained when first used. Any diagram must be of good quality and sources must be acknowledged appropriately.
Total 100

Referencing Style American Psychological Association (APA) or Harvard (author-date)
Submission Online

Learning Outcomes Assessed
This section can be expanded to view the assessed learning outcomes

1. Recognise and describe the differing ways in which drugs and chemicals act quantitatively and qualitatively on living organisms.

2. Recall and explain the basic priciples of pharmacology - pharmacodynamics, pharmacokinetics, drug design and clinical trials.

3. Recall and classify the major groups of medicines with respect to pathophysiology, their actions and therapeutic applications for medical science, paramedic science and podiatry practice (including local and general anaesthesia, cardiovascular, CNS, gastrointestinal, antimicrobial, respiratory and endocrine).

5. Appraise the scientific literature relating to drugs and medicines and communicate this knowledge to your peers

Graduate Attributes
This section can be expanded to view the assessed graduate attributes

1. Communication

3. Critical Thinking

4. Information Literacy

6. Information Technology Competence

7. Cross Cultural Competence



2 Written Assessment

Assessment Title Written Assessment - Computer-aided learning practicals
Task Description

This task requires the completion of Moodle lessons/Computer-aided learning (CAL) modules and associated questions. This item will help with study of several fundamental aspects of basic pharmacology. These should be seen as part of the simulated practical learning component of the course and are linked to background tasks which will enhance completion of Assessment item #3. This item will be available to complete from week 5.

Assessment Due Date Week 8 Thursday (04-May-2017) 11:00 PM AEST
Return Date to Students Week 10 Thursday (18-May-2017)
Weighting 15%
Assessment Criteria

This task requires completion of the Moodle lessons/CAL modules - these items have questions to be completed and will be marked either correct or incorrect.

Referencing Style American Psychological Association (APA) or Harvard (author-date)
Submission Online

Learning Outcomes Assessed
This section can be expanded to view the assessed learning outcomes

2. Recall and explain the basic priciples of pharmacology - pharmacodynamics, pharmacokinetics, drug design and clinical trials.

3. Recall and classify the major groups of medicines with respect to pathophysiology, their actions and therapeutic applications for medical science, paramedic science and podiatry practice (including local and general anaesthesia, cardiovascular, CNS, gastrointestinal, antimicrobial, respiratory and endocrine).

4. Understand how pharmacological laboratory experiments are conducted by using computer aided learning modules, and interpret the results from these experiments (tables/graphs).

Graduate Attributes
This section can be expanded to view the assessed graduate attributes

2. Problem Solving

3. Critical Thinking

6. Information Technology Competence



3 Written Assessment

Assessment Title Written Assessment - complex reasoning
Task Description

Practical literature review

This is a single assessment task worth a total of 25%. This assignment encourages the synthesis of literature sources and current scientific information on significant areas of human system functioning and subsequent pharmacological intervention together with sound mechanistic knowledge from the CAL modules. This is an imaginary drug to base your written assessment item on and should build on the knowledge from the CAL modules.

Students only need to pick ONE of the following imaginary drugs to complete this assessment item.

Our old friend Dr Magoo has turned his hand to science rather than medicine following his recent legal liability case from BMSC12010. Dr Magoo has just designed three new drugs - Pressorchol, Intestocalm and Surgysleep.

  • Pressorchol is thought to help manage hypertension and decrease cholesterol
  • Intestocalm is a revolutionary new antispasmodic agent for the intestine which stops GIT muscle contractions
  • Surgysleep is a wonder anaesthetic and analgesic with few side effects (minimal respiratory depression with almost immediate recovery)

Your task is to help Dr Magoo figure out how this drug might be working (mechanism(s) of action) by describing a series of experiments you could use to test this compound. A good place to start would be experimental techniques we have covered in the CALs. It would be advantageous to discuss existing compounds that might have similar properties.

A passing mark would require at least 10 primary references and students should consider their own positioning on the topic chosen. This means that the reader should be able to understand from your perspective the theoretic and practical basis of this compound. The word limit for this task is approximately 3000 but is flexible on the higher side. This item requires the student to hypothesize about the possible implications and mechanisms of action.

Assessment Due Date Week 10 Friday (19-May-2017) 11:00 PM AEST
Return Date to Students Week 12 Friday (02-Jun-2017)
Weighting 25%
Assessment Criteria

The following criteria and marking scheme will be used to evaluate the review:

Section Marks Criteria
Topic/Title/Content 30 The review should state clearly the topic/intervention to be reviewed together with sufficient supporting evidence (references). Statements should be appropriately referenced and ideas should flow in a logical manner. Examination of simulated experiments should be included.
Referencing 10 All articles referred to in the review need to be listed in this section. Referencing style should follow the “Harvard” style as described in the website listed in the assignments section of this Course Profile. It is estimated that a minimum of 10 journal articles will be required. Currency of the journals articles is important.
Positioning of review/Discussion 30 The implications of the drug should be discussed – how do you think it may work? Your own judgement should also be included.
Writing style/Presentation 30 The document should be word processed and printed on a good quality printer. Reviews should be clearly written in full sentences (not points) using correct spelling and grammar. Abbreviations should be explained when first used.
Total 100

Referencing Style American Psychological Association (APA) or Harvard (author-date)
Submission Online

Learning Outcomes Assessed
This section can be expanded to view the assessed learning outcomes

1. Recognise and describe the differing ways in which drugs and chemicals act quantitatively and qualitatively on living organisms.

2. Recall and explain the basic priciples of pharmacology - pharmacodynamics, pharmacokinetics, drug design and clinical trials.

5. Appraise the scientific literature relating to drugs and medicines and communicate this knowledge to your peers

Graduate Attributes
This section can be expanded to view the assessed graduate attributes

1. Communication

2. Problem Solving

3. Critical Thinking

4. Information Literacy

5. Team Work

6. Information Technology Competence

7. Cross Cultural Competence

8. Ethical practice



Examination

Outline Complete an examination
Date During the University examination period
Weighting 50%
Condition Minimum percentage of examination marks required to pass course - 40%
Length 180 minutes
Details Dictionary - non-electronic, concise, direct translation only (dictionary must not contain any notes or comments).
Calculator - non-programmable, no text retrieval, silent only.
Closed Book
Learning Outcomes Assessed
This section can be expanded to view the assessed learning outcomes

1. Recognise and describe the differing ways in which drugs and chemicals act quantitatively and qualitatively on living organisms.

2. Recall and explain the basic priciples of pharmacology - pharmacodynamics, pharmacokinetics, drug design and clinical trials.

3. Recall and classify the major groups of medicines with respect to pathophysiology, their actions and therapeutic applications for medical science, paramedic science and podiatry practice (including local and general anaesthesia, cardiovascular, CNS, gastrointestinal, antimicrobial, respiratory and endocrine).

Graduate Attributes
This section can be expanded to view the assessed graduate attributes

1. Communication

2. Problem Solving

3. Critical Thinking


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