BIOL12106 - Molecular Biology
Term 1 - 2017


All details in this unit profile for BIOL12106 have been officially approved by CQUniversity and represent a learning partnership between the University and you (our student). The information will not be changed unless absolutely necessary and any change will be clearly indicated by an approved correction included in the profile.

Overview

This unit focuses on developing an understanding of how genomes are organised, how they function within the cell, how molecular medical treatments can be developed, ways in which we can manipulate genomes and utilise their components for a range of purposes including medical, agricultural, and commercial.

Details

Career Level Undergraduate
Unit Level Level 2
Credit Points 6
Student Contribution Band 7A
Fraction of Full-Time Student Load 0.125

Pre-requisites or Co-requisites

Prerequisites

ZOOL11005 Foundation Animal Biology

or

BIOL11100 Functional Biology

or

BMSC11003 Introduction to Medical Sciences

or

BMSC11004 Introduction to Biochemistry

or

BMSC11005 Foundations of Biochemistry

or

BMED19010 Macromolecules and Cell Function

Residential Schools

This unit has a Compulsory Residential School for distance mode students and the details are:
Click here to see your Residential School Timetable.

Attendance Requirements

All on-campus students are expected to attend scheduled classes – in some units, these classes are identified as a mandatory (pass/fail) component and attendance is compulsory. International students, on a student visa, must maintain a full time study load and meet both attendance and academic progress requirements in each study period (satisfactory attendance for International students is defined as maintaining at least an 80% attendance record).

Offerings

Term 1 - 2017
  • Mixed Mode
  • Rockhampton

Website

This unit has a website, within the Moodle system, which is available two weeks before the start of term. It is important that you visit your Moodle site throughout the term. Go to Moodle

Recommended Student Time Commitment

Each 6-credit Undergraduate unit at CQUniversity requires an overall time commitment of an average of 12.5 hours of study per week, making a total of 150 hours for the unit.

Class Timetable

Assessment Overview

Assessment Task Weighting
1. Written Assessment 20%
2. Practical and Written Assessment 20%
3. Examination 60%

This is a graded unit: your overall grade will be calculated from the marks or grades for each assessment task, based on the relative weightings shown in the table above. You must obtain an overall mark for the unit of at least 50%, or an overall grade of ‘pass’ in order to pass the unit. If any ‘pass/fail’ tasks are shown in the table above they must also be completed successfully (‘pass’ grade). You must also meet any minimum mark requirements specified for a particular assessment task, as detailed in the ‘assessment task’ section (note that in some instances, the minimum mark for a task may be greater than 50%). Consult the University’s Grades and Results Procedures for more details of interim results and final grades.

All University policies are available on the IMPortal.

You may wish to view these policies:

  • Grades and Results Procedure
  • Assessment Policy and Procedure (Higher Education Coursework)
  • Review of Grade Procedure
  • Academic Misconduct Procedure
  • Monitoring Academic Progress (MAP) Policy and Procedure – Domestic Students
  • Monitoring Academic Progress (MAP) Policy and Procedure – International Students
  • Refund and Excess Payments (Credit Balances) Policy and Procedure
  • Student Feedback – Compliments and Complaints Policy and Procedure
  • Acceptable Use of Information and Communications Technology Facilities and Devices Policy and Procedure

This list is not an exhaustive list of all University policies. The full list of University policies are available on the IMPortal.

Feedback, Recommendations and Responses

Every unit is reviewed for enhancement each year. At the most recent review, the following staff and student feedback items were identified and recommendations were made.

Feedback Source Recommendation
One suggestion was to have a few more links to articles and youtube videos for extra material to support learning objectives each week. Course Evaluation The Course Coordinator will aim to include these at the next offering by including a link to additional online material on each set of lecture slides.
On successful completion of this unit, you will be able to:
  1. Demonstrate a clear understanding of the structure, organisation, utility and isolation of nucleic acids
  2. Demonstrate a clear understanding of the principles of gene cloning and sequencing
  3. Accurately review and evaluate the strategies associated with the transformation of micro-organisms, plants and animals
  4. Demonstrate safe and efficient laboratory skills in molecular biology
  5. Demonstrate knowledge on the applications of molecular biology skills to medical molecular biology

Alignment of Assessment Tasks to Learning Outcomes

Assessment Tasks Learning Outcomes
1 2 3 4 5
1 - Written Assessment        
2 - Practical and Written Assessment      
3 - Examination  

Alignment of Graduate Attributes to Learning Outcomes

  • Introductory Level
  • Intermediate Level
  • Graduate Level
Graduate Attributes Learning Outcomes
1 2 3 4 5
1. Communication    
2. Problem Solving      
3. Critical Thinking          
4. Information Literacy        
5. Team Work        
6. Information Technology Competence          
7. Cross Cultural Competence          
8. Ethical practice        

Alignment of Assessment Tasks to Graduate Attributes

  • Introductory Level
  • Intermediate Level
  • Graduate Level
Assessment Tasks Graduate Attributes
1 2 3 4 5 6 7 8
1 - Written Assessment            
2 - Practical and Written Assessment          
3 - Examination              

Prescribed Textbooks

Fundamental Molecular Biology
Author/s: Allison LA Year: 2012
Edition: 2 Publisher: Wiley
City: Hoboken State: NJ
Country: USA
View textbooks at the CQUniversity Bookshop

IT Resources

You will need access to the following IT resources:
  • CQUniversity Student Email
  • Internet
  • Unit Website (Moodle)
All submissions for this unit must use the Harvard (author-date) referencing style (details can be obtained here). For further information, see the Assessment Tasks below.
Unit CoordinatorWilliam Aspden (w.aspden@cqu.edu.au)
Note: Check the Term-Specific section for any additional contact information provided by the teaching team
Week Begin Date Module/Topic Chapter Events and Submissions
Week 1 06-03-2017

Introduction to molecular biology (Ch1, p1-15)

Online slides & text as indicated

Week 2 13-03-2017

DNA structure (Ch2 p17-31); replication (Ch6 p121-123); PCR (Ch8 p205-206; Ch9 p245)

Online slides & text as indicated

Week 3 20-03-2017

RNA (Ch3 p39-45) transcription/translation (Fig 11.2 p294)

Online slides & text as indicated

Week 4 27-03-2017

Genome organisation (Ch 5 p91-108)

Online slides & text as indicated

Week 5 03-04-2017

Nucleotide isolation & characterisation, electrophoresis (Ch 8 p215-216)

Online slides & text as indicated

Vacation Week 10-04-2017
Week 6 17-04-2017

Sequencing DNA (Chap 8 p220-223)

Online slides & text as indicated

Week 7 24-04-2017

Molecular cloning of DNA (Ch8 p190-199)

Online slides and text as indicated

Week 8 01-05-2017

Genetically modified organisms (Ch15 p479-509)

Online slides and text as indicated

Essay Due Friday (05 May 17) 04:00 PM AEST
Week 9 08-05-2017

Gene therapies (Ch17 p566-579)

Online slides and text as indicated

Week 10 15-05-2017

High throughput analyses (Ch 16 p529-533)

Online slides and text as indicated

Week 11 22-05-2017

Epigenetics (Ch 12 Summary, P398-400)

Online slides and text as indicated

Week 12 29-05-2017

Human Microbiome Project

Online slides and web searches.

Review/Exam Week 05-06-2017
Exam Week 12-06-2017

The Residential School is compulsory to attend, for all enrolled students.

1 Written Assessment

Assessment Title Essay
Task Description

Gene Therapy seems to be an important area in modern medical research. Choose one clinical area of gene therapy research for your essay and undertake literature searches for information on the developments, status and challenges on your chosen topic. If you wish you may compare the gene therapy approaches with other treatment modalities.

You may either cover a broad area in a category (e.g. gene therapy research for cancers) or be more specific in your approach (e.g. gene therapy research for a specific type of cancer).

Using secondary (review articles, text books) and at least five recent (last 10 years) primary literature articles, investigate and report on this topic.

Length 1000-1500 words (not including reference list ) 12 point, 1 1/2 line spacing.

Assessment Due Date Week 8 Friday (05-May-2017) 04:00 PM AEST
Return Date to Students Week 10 Friday (19-May-2017)
Weighting 20%
Assessment Criteria

Assessment criteria

Title: Write a descriptive, scientific title for the essay. Try and give your work a title that is appropriate to what your final work represents. (1 mark)

Introduction: A one paragraph lead-in to immediately capture attention and indicate the material you will cover. (2 marks)

Discussion: Thorough review of literature on your topic area written in your own words. Logically organised. (10 marks)

Conclusions: In one paragraph summarise the status of the research you have reviewed in this area and any future research directions. (2 marks)

References: Cite and list all references referred to in your essay. Marks will be awarded for reference quality, citing within the report and listing references correctly at the end of the report. (2 marks)

Spelling, Grammar, Style: Accuracy. (3 marks)

Conditions Minimum mark or grade - 50% (10/20)
Referencing Style Harvard (author-date)
Submission Online

via Assessment Block in Course Moodle Site

Learning Outcomes Assessed
This section can be expanded to view the assessed learning outcomes

5. Demonstrate knowledge on the applications of molecular biology skills to medical molecular biology

Graduate Attributes
This section can be expanded to view the assessed graduate attributes

3. Critical Thinking

4. Information Literacy



2 Practical and Written Assessment

Assessment Title Practical Report
Task Description

Undertake and show Residential School experimental calculations, report experimental results and answer questions provided. Answers to be succinct. Students may submit one such report per pair (2) of students. Clearly label report with student names and student numbers.

Assessment Due Date Submit at the end of the Residential School.
Return Date to Students Week 9 Friday (12-May-2017)
Weighting 20%
Assessment Criteria

Assessment will be based on the accuracy of calculations and correctness of answers to questions.

Conditions Minimum mark or grade - 50% (10/20)
Referencing Style Harvard (author-date)
Submission Hard copy
Group submission

Hand in at end of Residential School

Learning Outcomes Assessed
This section can be expanded to view the assessed learning outcomes

1. Demonstrate a clear understanding of the structure, organisation, utility and isolation of nucleic acids

4. Demonstrate safe and efficient laboratory skills in molecular biology

Graduate Attributes
This section can be expanded to view the assessed graduate attributes

1. Communication

3. Critical Thinking

5. Team Work



Examination

Outline Complete an examination
Date During the University examination period
Weighting 60%
Length 120 minutes
Details Dictionary - non-electronic, concise, direct translation only (dictionary must not contain any notes or comments).
Calculator - non-programmable, no text retrieval, silent only.
Closed Book
Learning Outcomes Assessed
This section can be expanded to view the assessed learning outcomes

1. Demonstrate a clear understanding of the structure, organisation, utility and isolation of nucleic acids

2. Demonstrate a clear understanding of the principles of gene cloning and sequencing

3. Accurately review and evaluate the strategies associated with the transformation of micro-organisms, plants and animals

5. Demonstrate knowledge on the applications of molecular biology skills to medical molecular biology

Graduate Attributes
This section can be expanded to view the assessed graduate attributes

1. Communication


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